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IJC-B Vol.47B [2008] >
IJC-B Vol.47B(05) [May 2008] >


Title: Synthesis and nematicidal activity of 2-(1H-benzo[d]imidazol-2-ylmethyl)-4- aryl-1-thia-4-azaspiro[4.5]decan-3-one
Authors: Srinivas, A
Nagaraj, A
Reddy, Ch Sanjeeva
Keywords: Spirothiazolidinone
Benzimidazole
Antibacterial activity
Antifungal activity
Nematicidal activityNematicidal activity
Issue Date: May-2008
Publisher: CSIR
Abstract: A series of N-cyclohexylidene-N-phenylamines 3 are prepared by the condensation of cyclohexanone 1 with aryl amine 2, subsequent treatment of 3 with thiomalic acid give the corresponding 2-(3-oxo-4-aryl-1-thia-4- azaspiro[4.5]dec-2-yl)acetic acid 4, which on reaction with o-phenylenediamine give 2-(1H-benzo[d]imidazol-2-ylmethyl)- 4-aryl-1-thia-4-azaspiro[4.5]decan-3-one 5. Characterization of all the compounds has been done by IR, ¹H NMR, MS and elemental analyses. The antibacterial, antifungal and nematicidal activities of the compounds have also been evaluated.
Page(s): 787-791
ISSN: 0376-4699
Source:IJC-B Vol.47B(05) [May 2008]

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