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|Title:||Synthesis and nematicidal activity of 2-(1H-benzo[d]imidazol-2-ylmethyl)-4- aryl-1-thia-4-azaspiro[4.5]decan-3-one|
Reddy, Ch Sanjeeva
|Keywords:||Spirothiazolidinone;Benzimidazole;Antibacterial activity;Antifungal activity;Nematicidal activityNematicidal activity|
|Abstract:||A series of N-cyclohexylidene-N-phenylamines 3 are prepared by the condensation of cyclohexanone 1 with aryl amine 2, subsequent treatment of 3 with thiomalic acid give the corresponding 2-(3-oxo-4-aryl-1-thia-4- azaspiro[4.5]dec-2-yl)acetic acid 4, which on reaction with o-phenylenediamine give 2-(1H-benzo[d]imidazol-2-ylmethyl)- 4-aryl-1-thia-4-azaspiro[4.5]decan-3-one 5. Characterization of all the compounds has been done by IR, ¹H NMR, MS and elemental analyses. The antibacterial, antifungal and nematicidal activities of the compounds have also been evaluated.|
|Appears in Collections:||IJC-B Vol.47B(05) [May 2008]|
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