Please use this identifier to cite or link to this item:
Title: Synthesis of novel naphtho[2,1-b]furo[3,2-b]pyridine derivatives as potential antimicrobial agents
Authors: Ramesh, D
Chandrashekhar, C
Vaidya, V P
Keywords: Naphthofuran
Thrope-Zielger reaction
Friedlander reaction
Antimicrobial activity
Issue Date: May-2008
Publisher: CSIR
Abstract: The starting materials 2-acyl-3-aminonaphtho[2,1-b]furans 4a-b have been directly synthesized from 2-hydroxy-1-naphthaldehyde oxime by treating with α-haloketone through Thrope-Ziegler reaction. The compounds 4a-b undergo Friedlander cyclization on treatment with active methylene compounds, and produce title compounds 5a-b, 6a-b and 7a-b. Some other routes for the synthesis of various derivatives of this new heterocycle have been investigated. All the newly synthesized compounds are characterized by elemental analysis, spectral studies, and have been evaluated for antimicrobial activity.
Description: 753-758
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.47B(05) [May 2008]

Files in This Item:
File Description SizeFormat 
IJCB 47B(5) 753-758.pdf192.38 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.