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http://nopr.niscair.res.in/handle/123456789/17218
Title: | Potentiality of a new compound for in vitro differentiation between halophilic and non-halophilic vibrios |
Authors: | Ray, R Das, A K Dutta, N K Chakrabarty, A N Chaudhuri, B N Seth, S Dastidar, Sujata G |
Issue Date: | Feb-2002 |
Publisher: | NISCAIR-CSIR, India |
Abstract: | Sensitivity of 21 halophilic vibrios and 16 clinical isolates of non-halophilic vibrios was determined against a new possible antivibrio agent, a pyrimidine analogue, 4, 6-dimethylpyrimidine -2-thiol (4,6-DMPT). It appeared to be a vibriocidal agent, having a mean MIC and MBC of 32 μg/ml for halophilic strains and 64 μg/ml for non-halophilic strains and an LD50of 300 mg/Kg body weight of mice. Thus, 4,6-DMPT may help an in vitro distinction between halophilic and non-halophilicvibrios. Sensitivity of these strains was also studied with respect to pteridine, crystal violet and Tween 80 hydrolysis as further markers distinguishing between these 2 groups which could also be differentiated by their growth on TCBS or/and CLED media. |
Page(s): | 220-222 |
URI: | http://hdl.handle.net/123456789/17218 |
ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
Appears in Collections: | IJEB Vol.40(02) [February 2002] |
Files in This Item:
File | Description | Size | Format | |
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IJEB 40(2) 220-222.pdf | 635.75 kB | Adobe PDF | View/Open |
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