Please use this identifier to cite or link to this item:
|Title:||Effect of arsenic on cell growth of the cellular slime mould, Dictyostelium discoideum|
|Keywords:||Arsenic;Dictyostelium discoideum;Cell growth|
|Abstract:||The growing D. Discoideum cells were killed in a dose-dependent manner when exposed to 100 and 140ppm of arsenic(As2O3) at mid-log phase for 20 min. Reduced plaque sizes and changed cell and colony morphologies were observed in the treated cells. Endocytotic functions (both phagocytosis and pinocytosis) were also inhibited in the treated cells. Arsenic treated cell showed a lower DNA and protein synthetic activities. These findings are discussed in relation to known mechanism of action of the heavy metal on growth-related cellular functions.|
|ISSN:||0975-1009 (Online); 0019-5189 (Print)|
|Appears in Collections:||IJEB Vol.41(11) [November 2003]|
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.