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Title: Effect of arsenic on cell growth of the cellular slime mould, Dictyostelium discoideum
Authors: Mukhopadhyay, S
Chatterjee, S
Keywords: Arsenic;Dictyostelium discoideum;Cell growth
Issue Date: Nov-2003
Publisher: NISCAIR-CSIR, India
Abstract: The growing D. Discoideum cells were killed in a dose-dependent manner when exposed to 100 and 140ppm of arsenic(As2O3) at mid-log phase for 20 min. Reduced plaque sizes and changed cell and colony morphologies were observed in the treated cells. Endocytotic functions (both phagocytosis and pinocytosis) were also inhibited in the treated cells. Arsenic treated cell showed a lower DNA and protein synthetic activities. These findings are discussed in relation to known mechanism of action of the heavy metal on growth-related cellular functions.
Page(s): 1300-1305
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.41(11) [November 2003]

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