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Title: Differential organization of a LINE-1 family in Indian pygmy field mice
Authors: Chatterjee, B
Bahadur, M
Srivastava, S
Sharma, T
Issue Date: Jan-2003
Publisher: NISCAIR-CSIR, India
Abstract: Southern blot hybridization analysis of genomic DNAs digested with restriction endonuclease   EcoR I and Ava II from Mus musculus domesticus, Mus booduga and Mus terricolor with a cloned repetitive DNA fragment of Mus booduga as a probe showed difference in restriction pattern of this DNA in these three species. Further Southern analysis of the BamH I digested genomic DNAs from these species hybridized with cloned DNA fragment as a probe and sequencing of the cloned DNA revealed that this 252 bp cloned DNA fragment is a part of BamHI repeat element of genus Mus and is 87 % homologous to the contiguous portion of the Mus musculus domesticus LlNE- 1 element. The species specific fragment pattern generated by different restriction endonucleases using this DNA as a probe revealed difference in the organization of  LlNE- 1 repetitive element in the three species of genus Mus.
Page(s): 53-57
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.41(01) [January 2003]

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