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|Title:||Design, synthesis and neuropharmacological activity of dihydro imidazole derivatives|
Haldar, P K
|Keywords:||Dihydroimidazole;Anticonvulsant;CNS depressant;Nasal decongestant|
|Abstract:||A new series of dihydro imidazole derivatives have been synthesized and characterized by UV-Vis, IR, 1H NMR and mass spectroscopy. The synthesized compounds have been screened for neuro pharmacological activities. All the compounds are effective; amongst them compound 8 shows more prominent anticonvulsant and CNS depressant property. The standard drug diazepam at 25 mg / kg i.p. has been used for comparison. The results are statistically treated for their significance at p<0.05 and p<0.01 level.|
|Appears in Collections:||IJC-B Vol.52B(04) [April 2013]|
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