Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/16626
Title: Synthesis of purines and azapurines
Authors: Shishoo, C J
Jain, K S
Jain, S R
Shirsath, V S
Ravikumar, T
Issue Date: Sep-1999
Publisher: NISCAIR-CSIR, India
Abstract: The synthesis of a series of C(8) unsubstituled (11a-h), C(8) substituted (12a-e), 8-mercapto (13a-e) 1,3-diaryl-2- thioxanthines, as well as, 8-aza-1,3-diaryl-2-thioxanthines 14a-g, through precursors, 5,6-diamino-1,3-diaryl-2-thiouracils 10 has been reported. Recently, the synthesis of a novel series of 6-amino-1,3-diaryl-2-thiouracils 8 under the influence of dry HCI gas has been reported. 14.15. These compounds are converted to the requisite 5,6-diamino-1,3-diaryl-2-thiouracils 10 via reduction of an intermediate 5-nitroso-6-amino-1,3-diaryl-2-thiouracils 9. Cyclocondensation of 5,6-diamino-2- thiouracils 10 with appropriate one carbon donors afford the desired purines 11-13.
Page(s): 1052-1065
URI: http://hdl.handle.net/123456789/16626
Appears in Collections:IJC-B Vol.38B(09) [September 1999]

Files in This Item:
File Description SizeFormat 
IJCB 38B(9) 1052-1065.pdf2.1 MBAdobe PDFView/Open


Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.