Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/16572
Title: An efficient method to chiral β-hydroxy acids: Synthesis of lipid-A side chain
Authors: Nandanan, E
Phukan, Prodeep
Sudalai, A
Issue Date: Aug-1999
Publisher: NISCAIR-CSIR, India
Abstract: The synthesis of optically active β-hydroxy acids 5a-c is achieved in four steps from their corresponding terminal olefins 1a-c by employing Sharpless asymmetric dihydroxylation. The regioselective ring opening of chiral cyclic sulfites 3a-c with cyanide ion, constitutes the key reaction, thus producing the hydroxy nitriles 4a-c.
Page(s): 893-896
URI: http://hdl.handle.net/123456789/16572
Appears in Collections:IJC-B Vol.38B(08) [August 1999]

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