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Title: Ultrasonic study of 5H-dibenz[B,F]azepine-5-carboxamide and 7-chloro-1,5-dihydro-1-methyl-5-phenyl-1,5-benzodiazepine-2,4(3H)-dione
Authors: Ravi, S
Indira, S
Natchimuthu, V
Sengottaiyan, C
Keywords: Ultrasonic velocity;Carbamazepine;Clobazam;Structure factor
Issue Date: Apr-2013
Publisher: NISCAIR-CSIR, India
Abstract: The experimental ultrasonic velocity has been measured for anticonvulsants such as Carbamazepine(CBZ), Oxycarbazepine(OXYCBZ) and Clobazam. The drugs are some of the most preferred for almost any kind of seizure. The highly non-soluble nature of such drugs in water might have not encouraged people to estimate the speed of sound through these drugs. In the present paper, based on the solubility of these drugs in DMSO (dimethylsulphoxide), water is gradually added to obtain different concentrations. The sound velocity is measured using 1 and 3 MHz interferometer specifically at room temperature. The sound velocity data is used to estimate the structural parameter which in turn exposes the similarity in behaviour of all the three drugs.
Page(s): 241-244
ISSN: 0975-1041 (Online); 0019-5596 (Print)
Appears in Collections:IJPAP Vol.51(04) [April 2013]

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