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|Title:||Microbiological degradation of a synthetic benzofurane type lactone|
Krstic, L J
|Abstract:||A benzofurane type lactone 4 incorporating an -methylene--butyrolactone moiety has been synthesized. The key steps involved are the Michael condensation of 4-dichloromethyl-4-methyl-2,5-cyclohexadienone 1 with dimethyl malonate and acetoxylation of 4-dichloromethyl-5-carboxymethyl-4-methyl-2-cyclohexenone 2 with lead (IV) acetate in BF3 -etherate which are indicative of the general route to -lactone. Microbial degradations of the synthetic benzofurane type lactone 4 have also been studied using Aspergillus niger. Saccharomyces cerevisiae, Bacillus mycoides, Agrobacterium and The lactone acts both as an additive for the nutrient substrate and as a source of organic carbon.|
|Appears in Collections:||IJC-B Vol.38B(02) [February 1999]|
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