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Title: Rapid access of some trisubstituted imidazoles from benzil condensed with aldehydes and ammonium acetate catalyzed by L-cysteine.
Authors: Roy, H N
Rahman, M M
Pramanick, P K
Keywords: Multicomponent reaction;Solventless condition;L-cysteine;2,4,5-trisubstituted imidazoles
Issue Date: Jan-2013
Publisher: NISCAIR-CSIR, India
Abstract: A simple highly versatile and efficient synthesis of 2,4,5-trisubstituted imidazole is achieved by three component cyclo-condensation of benzil, substituted aromatic aldehyde and ammonium acetate by l-cysteine as organocatalyst under solvent free condition. The key advantages of this process are high yields, cost effectiveness catalyst, easy purification technique and above all environmentally benign.
Page(s): 153-159
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.52B(01) [January 2013]

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