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Title: Antioxidant potential of pepper (Piper nigrum Linn.) leaves and its antimicrobial potential against some pathogenic microbes
Authors: Shanmugapriya, K
Saravana, P S
Payal, Harsha
Mohammed, S Peer
Williams, Binnie
Keywords: Pepper;Piper nigrum;Phytochemical;Antioxidant;Antimicrobial;Minimum Inhibitory Concentration;Microbes
Issue Date: Dec-2012
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl. (2011.01)—A61K 36/00.
Abstract: Medicinal plants represent a rich source of antimicrobial agents and used medicinally in different countries as source of many potent and powerful drugs. The present study was undertaken to evaluate phytochemical constituents, antimicrobial and antioxidant activities in three different solvents of pepper (Piper nigrum Linn.) leaves by standard methods. The phytochemical analysis revealed the presence of alkaloids, phenolic compounds, flavonoids and saponins expect tannins in all solvents. Antimicrobial activity was evaluated against clinically important bacteria, yeast and fungal strains using agar disc diffusion method. The results showed that the antimicrobial activity was more effective in acetone and ethyl acetate fractions of leaf extract than aqueous fractions and Minimum Inhibitory Concentrations were also determined. The phytochemical extracts of pepper showed potent antioxidant activity which was determined by free radical scavenging method. The pepper leaves extract showed high effect of the antioxidant activity due to the presences of phenolic content.
Page(s): 570-577
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.3(4) [December 2012]

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