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Title: Antimicrobial efficacy of Bridelia retusa (Linn.) Spreng. and Asclepias curassavica Linn.
Authors: Kurdekar, Ranjita R
Hegde, Ganesh R
Hebbar, Satyanarayana S
Keywords: Asclepias curassavica;Bridelia retusa;Ethnomedicine;Antimicrobial;Cold percolation;Soxhlet extraction
Issue Date: Dec-2012
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl. (2011.01)—A61K 36/00
Abstract: The in vitro bioassay of the bark extracts of Bridelia retusa Spreng. and root extracts of Asclepias curassavica Linn. was done by cold percolation and Soxhlet method against four bacterial species, viz. Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus vulgaris and two fungal species Candida albicans and Aspergillus niger. The MIC and MBC values for the extracts obtained by both the methods were tested separately. The acetone extract of B. retusa showed MIC values ranging from 25, 42.5 to 85 mg/mL against the tested strains where as the bactericidal and fungicidal concentrations were found to be ≥170 mg/mL. The MIC value for root extract of A. curassavica was 3.06 mg/mL and the bactericidal concentration was found to be 100 mg/mL. The present work is an attempt to justify that the method of extraction influences the efficacy of the plant extracts.
Page(s): 589-593
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.3(4) [December 2012]

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