Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/15559
Title: Screening of intestinal transit time of Euphorbia fusiformis Buch.- Ham. ex D. Don in Swiss albino mice
Authors: Ashok, B K
Bhat, Savitha D
Ravishankar, B
Keywords: Albino mice;Euphorbia fusiformis;Intestinal transit;Kaolin;Purgative;Virechana drug;Vishanika
Issue Date: Dec-2012
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl. (2011.01) - A61K 36/47, A61K 125/00, A61P 1/10
Abstract: Effect of Euphorbia fusiformis Buch.-Ham. ex. D. Don root powder on intestinal transit time was carried out after standardizing the kaolin expulsion test by administering 40% kaolin to overnight fasted Swiss albino mice. Evaluation on intestinal transit time was carried out by using this standard procedure by administering the drug at 130 mg/kg and 260 mg/kg doses. E. fusiformis root powder significantly shortened the duration required for the expulsion of kaolin in dose dependant manner. The study shows that the root powder of E. fusiformis possesses significant intestinal motility enhancing effect, the exact mechanism of which needs to be elucidated.
Page(s): 547-550
URI: http://hdl.handle.net/123456789/15559
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.3(4) [December 2012]

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