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Title: Multiple isoforms of protein kinase C in lymphocytes and airway smooth muscle of guinea pig
Authors: Fatma, Sumbul
Mushinski, J Frederic
Bansal, Surendra Kumar
Issue Date: Aug-2001
Publisher: NISCAIR-CSIR, India
Abstract: The isoenzyme pattern of protein kinase C (PKC) in lymphocytes and airway smooth muscles (ASM) was examined by Wes tern blot using commercially available monoclonal antibodies. The results showed the presence of PKC α, β, γ, ε, η, μ and ζ  in lymphocytes and PKC α,  γ, ε, η and ζ in ASM. The unexpected feature was the presence of PKC γ in both lymphocytes and ASM of guinea pigs. Expression of this PKC isoform is usually restricted to tissues in the central nervous system or spinal cord. Expression of PKC δ, θ, λ and τ was not detected in either lymphocytes or ASM.  
Page(s): 280-284
ISSN: 0975-0959 (Online); 0301-1208 (Print)
Appears in Collections:IJBB Vol.38(4) [August 2001]

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