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Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.51B [2012] >
IJC-B Vol.51B(12) December 2012] >
| Title: | An efficient synthesis of lactarochromal from 6-amino-2,2-dimethylchroman-4-one |
| Authors: | Kamat, Vijayendra P
Asolkar, Ratnakar N
Kirtany, Janardan K |
| Keywords: | Lactarochromal
Lactarius deliciosus
6-amino-2,2- dimethylchroman-4-one
6-iodo-2,2-dimethylchroman-4-one
N- formylpiperidine |
| Issue Date: | Dec-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Lactarochromal 1, a metabolite of Lactarius deliciosus, has been synthesised starting from
6-amino-2,2-dimethylchroman-4-one 3,
which in turn, is prepared from paracetamol via
the known intermediates. The amino compound 3 is then converted to the iodo compound 4, followed by formylation of the latter using N-formylpiperidine
to provide, efficiently, the natural product 1 in good yield. |
| Page(s): | 1761-1762 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.51B(12) December 2012]
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