Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/15200
Title: An efficient synthesis of lactarochromal from 6-amino-2,2-dimethylchroman-4-one
Authors: Kamat, Vijayendra P
Asolkar, Ratnakar N
Kirtany, Janardan K
Keywords: Lactarochromal
<i style="mso-bidi-font-style:normal"><span style="font-size:10.0pt;font-family:"Times New Roman";mso-fareast-font-family: "Times New Roman";mso-ansi-language:EN-GB;mso-fareast-language:EN-US; mso-bidi-language:AR-SA" lang="EN-GB">Lactarius deliciosus</span></i>
6-amino-2,2- dimethylchroman-4-one
6-iodo-2,2-dimethylchroman-4-one
N- formylpiperidine
Issue Date: Dec-2012
Publisher: NISCAIR-CSIR, India
Abstract: Lactarochromal <b style="mso-bidi-font-weight:normal">1</b>, a metabolite of <i style="mso-bidi-font-style: normal">Lactarius deliciosus</i>, has been synthesised starting from 6-amino-2,2-dimethylchroman-4-one <b style="mso-bidi-font-weight:normal">3,</b> which in turn, is prepared from paracetamol <i style="mso-bidi-font-style:normal">via </i>the known intermediates. The amino compound <b style="mso-bidi-font-weight: normal">3</b> is then converted to the iodo compound <b style="mso-bidi-font-weight: normal">4, </b>followed by formylation of the latter using N-formylpiperidine to provide, efficiently, the natural product <b style="mso-bidi-font-weight: normal">1 </b>in good yield.
Description: 1761-1762
URI: http://hdl.handle.net/123456789/15200
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.51B(12) December 2012]

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