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Title: Synthesis, characterisation and antimicrobial activity of 3-methyl-6-(aryl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine
Authors: Girisha, K S
Kalluraya, Balakrishna
Vidyashree, Jois H S
Keywords: 5-Azidopyrazole;Pyrazolopyridines;In situ Friedlaender reaction;Antimicrobial activity
Issue Date: Dec-2012
Publisher: NISCAIR-CSIR, India
Abstract: A series of 3-methyl-6-(aryl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine have been synthesized in one step by treating 5-azido-3-methyl-1-phenyl-1H-pyrazol-4-carboxaldehyde with suitably substituted acetophenones in basic medium. This reaction is a good example for in situ Friedlaender reaction. The newly synthesized compounds have been screened for their anti-microbial studies. All the compounds show MIC at low concentration itself against the tested fungi.
Page(s): 1767-1770
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.51B(12) December 2012]

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