Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/15193
Title: <span style="font-size:12.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-ansi-language: EN-GB;mso-fareast-language:EN-US;mso-bidi-language:AR-SA" lang="EN-GB">Acid catalyzed condensation of pyroglutamic acid with arylaldehydes: Synthesis of (3<i>R</i>, 7a<i>S</i>)-3-aryldihydropyrrolo[1, 2-<i>c</i>] oxazol-1, 5(3<i style="mso-bidi-font-style:normal">H</i>, 6<i style="mso-bidi-font-style:normal">H</i>) dione</span>
Authors: Prasad, Jagdish
Panday, Sharad Kumar
Keywords: Pyroglutamic acid
Aromatic aldehyde
Acid catalyzed condensation reaction
Bicyclic derivative
Issue Date: Dec-2012
Publisher: NISCAIR-CSIR, India
Abstract: A simple strategy for the synthesis of (3<i>R</i>, 7a<i>S</i>)-3-aryldihydro­pyrrolo [1, 2-<i>c</i>] oxazol-1, 5(3<i style="mso-bidi-font-style:normal">H</i>, 6<i style="mso-bidi-font-style: normal">H</i>)-diones as bicyclic hemi­aminals through acid catalyzed condensation of pyroglutamic acid with arylaldehydes has been described. This could be useful for the synthesis of complex natural products requiring α-substitution in proline or pyroglutamate skeleton.
Description: 1781-1784
URI: http://hdl.handle.net/123456789/15193
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.51B(12) December 2012]

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