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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
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Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.51B [2012] >
IJC-B Vol.51B(12) December 2012] >
| Title: | Acid catalyzed condensation of pyroglutamic acid with arylaldehydes: Synthesis of (3R, 7aS)-3-aryldihydropyrrolo[1, 2-c] oxazol-1, 5(3H, 6H) dione |
| Authors: | Prasad, Jagdish
Panday, Sharad Kumar |
| Keywords: | Pyroglutamic acid
Aromatic aldehyde
Acid catalyzed condensation reaction
Bicyclic derivative |
| Issue Date: | Dec-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A simple strategy for the
synthesis of (3R, 7aS)-3-aryldihydropyrrolo [1, 2-c]
oxazol-1, 5(3H, 6H)-diones as bicyclic hemiaminals through acid catalyzed
condensation of pyroglutamic acid with arylaldehydes has been described. This
could be useful for the synthesis of complex natural products requiring
α-substitution in proline or pyroglutamate skeleton. |
| Page(s): | 1781-1784 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.51B(12) December 2012]
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