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Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.51B [2012] >
IJC-B Vol.51B(12) December 2012] >
| Title: | A mild and efficient synthesis of bis(indolyl)methane derivatives catalyzed by monoammonium salt of 12-tungstophosphoric acid |
| Authors: | Giri, B Y
Devi, B L A Prabhavathi
Vijayalakshmi, K
Prasad, R B N
Lingaiah, N
Prasad, P S Sai |
| Keywords: | Indole
Bis(indolyl)methane
Aromatic aldehydes
Monoammonium salt
12-tungstophosphoric acid [(NH4)H2PW12O40]
Heteropolyacid |
| Issue Date: | Dec-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A simple, highly rapid and efficient
electophilic substitution reaction of indole with various aromatic aldehydes
has been carried out using 5 wt% of monoammonium salt of 12-tungstophosphoric
acid [(NH4)H2PW12O40] as a solid acid catalyst in acetonitrile to afford the corresponding
bis(indolyl)methanes in excellent yields (84-95%) at room temperature. The
heteropolyacid-based catalyst has the advantages of simple workup procedure,
water insolubility with good activity and high yielding reaction for the
synthesis of bis(indolyl)methane derivatives. |
| Page(s): | 1731-1737 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.51B(12) December 2012]
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