Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/15175
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dc.contributor.authorSalahdeen, Hussein M-
dc.contributor.authorIdowu, Gbolahan O-
dc.contributor.authorMurtala, Babatunde A-
dc.date.accessioned2012-12-08T15:24:48Z-
dc.date.available2012-12-08T15:24:48Z-
dc.date.issued2012-12-
dc.identifier.issn0975-1009 (Online); 0019-5189 (Print)-
dc.identifier.urihttp://hdl.handle.net/123456789/15175-
dc.description883-888en_US
dc.description.abstractTridax procumbens leaf extract induced aortic relaxation in a concentration-dependent manner, for both phenylephrine (PE) and KCl- induced contractions in isolated rat aortic rings. The relaxation effect of the extract on PE-induced contraction was 57% greater than that on KCl- induced contraction. The extract caused dose-dependent relaxations in precontracted isolated rat aorta with phenylephrine; the relaxation was attenuated by the removal of endothelium. However, the relaxation responses to sodium nitroprusside were not significantly abolished by the removal of endothelium. The vasorelaxatory effect of the extract was completely abolished in presence of L-NAME. The results indicate that the vasorelaxant effect of T. procumbens extract is probably mediated by both endothelium-dependent and-independent mechanisms.en_US
dc.language.isoen_USen_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJEB Vol.50(12) [December 2012]en_US
dc.subjectAcetylcholineen_US
dc.subjectAortic ringen_US
dc.subjectHypertensionen_US
dc.subjectSmooth muscleen_US
dc.subjectTridax procumbensen_US
dc.titleEndothelium-dependent and independent vasorelaxant effects of aqueous extract of Tridax procumbens Lin. leaf in rat aortic ringsen_US
dc.typeArticleen_US
Appears in Collections:IJEB Vol.50(12) [December 2012]

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