Please use this identifier to cite or link to this item:
http://nopr.niscair.res.in/handle/123456789/15173
Title: | Effect of long acting insulin supplementation on diabetic nephropathy in Wistar rats |
Authors: | Michael, Shiju Thomas Ganesh, Rajesh Nachiappa Viswanathan, Pragasam |
Keywords: | Diabetic nephropathy;Glargine;Long acting insulin;Rat model;Streptozotocin |
Issue Date: | Dec-2012 |
Publisher: | NISCAIR-CSIR, India |
Abstract: | This
study was designed to check whether insulin supplementation is crucial for
inducing diabetic nephropathy (DNP) in Wistar rats. Diabetes was induced by a
single intraperitoneal injection of streptozotocin. The urinary biochemical
parameters such as albumin, creatinine and urea nitrogen were monitored every
two weeks. The histological changes in the kidney were observed at the end of
both fifth and seventh month. Immunohistochemical analyses of VEGF, ERK-1 and
NF-![]() |
Page(s): | 867-874 |
URI: | http://hdl.handle.net/123456789/15173 |
ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
Appears in Collections: | IJEB Vol.50(12) [December 2012] |
Files in This Item:
File | Description | Size | Format | |
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IJEB 50(12) 867-874.pdf | 385.55 kB | Adobe PDF | View/Open |
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