NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.51B [2012] >
IJC-B Vol.51B(11) [November 2012] >


Title: Design, synthesis, biological evaluation of thiazolyl schiff base derivatives as novel anti-inflammatory agents
Authors: Bhosale, P P
Chavan, R S
Bhosale, A V
Keywords: Thiazole
Schiff base
Anti-inflammatory activity
Analgesic activity
Ulcerogenic activity
Issue Date: Nov-2012
Publisher: NISCAIR-CSIR, India
Abstract: ¬† A series of new 4-(4-substitutedphenyl)-N-(4-substituted¬≠benzylidene)-thiazol-2-amine derivatives 5a-l has been synthe¬≠sized and evaluated for their anti-inflammatory and analgesic activities at a dose of 50 mg/kg p.o. The most active compounds 5a, 5j have been subjected to acute ulcerogenesis study at a dose of 150 mg/kg. The structure of all these compounds have been established on the basis of spectral (IR, 1H NMR data) studies.
Page(s): 1649-1654
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.51B(11) [November 2012]

Files in This Item:

File Description SizeFormat
IJCB 51B(11) 1649-1654.pdf73.05 kBAdobe PDFView/Open
 Current Page Visits: 667 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 603548 since 06-Feb-2009  Last updated on 21-Oct-2014Webmaster: nopr@niscair.res.in