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Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.50 [2012] >
IJEB Vol.50(11) [November 2012] >
| Title: | Olfactory tract transection in neonatal rats: Evidence for Mitral cell regeneration and restoration of functional connectivity with its targets |
| Authors: | Anil, S P
Laxmi, T R
Kutty, Bindu M
Raju, T R |
| Keywords: | Local field potentials
Mitral cells
Olfactory tract transection
Piriform cortex
Regeneration |
| Issue Date: | Nov-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Central Nervous System (CNS) regeneration
and repair mechanism are two important aspects of functional recovery in the
adult central nervous system following brain and spinal cord injury. Following
olfactory tract transection in neonatal rats, functional connectivity between
the olfactory bulb and the piriform cortex gets re-established by 120 days. The
recovery of the dendritic morphology was associated with the synchronized
oscillatory activity between olfactory bulb and piriform cortex. Mitral cells
which were regenerated after the transection showed profuse branching,
indicative of their undifferentiated state. However, normal dendritic
morphology could be seen by 120 days after olfactory tract transection. These
results thus provide a supportive evidence for the restoration of the
functional connections between the olfactory bulb and the piriform cortex at
120 days. |
| Page(s): | 755-764 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.50(11) [November 2012]
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