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Indian Journal of Chemistry -Section A (IJC-A) >
IJC-A Vol.51A [2012] >
IJC-A Vol.51A(11) [November 2012] >
| Title: | Fluorescence and CD studies of protein denaturation in the presence of sub-picomolar gold nanoparticles |
| Authors: | Ojha, K
Chowdhury, P K
Ganguli, A K |
| Keywords: | Protein-nanoparticle interactions
Protein conformation
Protein denaturation
Thermal denaturation
Chemical denaturation
Nanoparticles
Gold nanoparticles
Fluorescence spectroscopy
Circular dichroism |
| Issue Date: | Nov-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The dependence of
nanoparticle concentration on the conformation of bovine serum albumin has been
studied. A very small but consistent enhancement in the tryptophan emission is
observed in the presence of sub-picomolar concentration of gold nanoparticles.
At this concentration, the bovine serum albumin unfolding profile in presence
and absence of nanoparticles are quite similar and the protein conformation
remains essentially conserved. |
| Page(s): | 1561-1566 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0975(Online); 0376-4710(Print) |
| Source: | IJC-A Vol.51A(11) [November 2012]
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