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http://nopr.niscair.res.in/handle/123456789/14892| Title: | Fluorescence and CD studies of protein denaturation in the presence of sub-picomolar gold nanoparticles |
| Authors: | Ojha, K Chowdhury, P K Ganguli, A K |
| Keywords: | Protein-nanoparticle interactions;Protein conformation;Protein denaturation;Thermal denaturation;Chemical denaturation;Nanoparticles;Gold nanoparticles;Fluorescence spectroscopy;Circular dichroism |
| Issue Date: | Nov-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The dependence of nanoparticle concentration on the conformation of bovine serum albumin has been studied. A very small but consistent enhancement in the tryptophan emission is observed in the presence of sub-picomolar concentration of gold nanoparticles. At this concentration, the bovine serum albumin unfolding profile in presence and absence of nanoparticles are quite similar and the protein conformation remains essentially conserved. |
| Page(s): | 1561-1566 |
| URI: | http://hdl.handle.net/123456789/14892 |
| ISSN: | 0975-0975(Online); 0376-4710(Print) |
| Appears in Collections: | IJC-A Vol.51A(11) [November 2012] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCA 51A(11) 1561-1566_Suppl Data.pdf | Supplementary data | 130.59 kB | Adobe PDF | View/Open |
| IJCA 51A(11) 1561-1566.pdf | Main article | 471.15 kB | Adobe PDF | View/Open |
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