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IJC-A Vol.51A [2012] >
IJC-A Vol.51A(11) [November 2012] >


Title: Fluorescence and CD studies of protein denaturation in the presence of sub-picomolar gold nanoparticles
Authors: Ojha, K
Chowdhury, P K
Ganguli, A K
Keywords: Protein-nanoparticle interactions
Protein conformation
Protein denaturation
Thermal denaturation
Chemical denaturation
Nanoparticles
Gold nanoparticles
Fluorescence spectroscopy
Circular dichroism
Issue Date: Nov-2012
Publisher: NISCAIR-CSIR, India
Abstract: The dependence of nanoparticle concentration on the conformation of bovine serum albumin has been studied. A very small but consistent enhancement in the tryptophan emission is observed in the presence of sub-picomolar concentration of gold nanoparticles. At this concentration, the bovine serum albumin unfolding profile in presence and absence of nanoparticles are quite similar and the protein conformation remains essentially conserved.
Page(s): 1561-1566
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-0975(Online); 0376-4710(Print)
Source:IJC-A Vol.51A(11) [November 2012]

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