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Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)] >
IJNPR Vol.3 [2012] >
IJNPR Vol.3(3) [September 2012] >
| Title: | Antioxidant activity of Hedychium spicatum Buch.- Ham. rhizomes |
| Authors: | Sravani, T Paarakh, Padmaa M |
| Keywords: | Hedychium spicatum Buch.-Ham. Antioxidant DPPH Gallic acid Ascorbic acid Phenol Flavonoid |
| Issue Date: | Sep-2012 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int. cl. (2011.01)—A61K 36/00, A61P 17/18 |
| Abstract: | The different
extracts of Hedychium spicatum Buch.-Ham. (Zingiberaceae) were
evaluated for antioxidant activity by
1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and reducing
power determination method. Total phenol and total flavonoid content in each
extracts were also determined. Gallic acid and ascorbic acid were used as
reference standards. They exhibited strong antioxidant DPPH radical scavenging
activity with IC50 value of 0.43, 259.1, 386.7, 414.3, 77.01 and
51.54 μg/mL for gallic acid, petroleum ether, benzene, chloroform, methanol and
aqueous extracts of rhizomes of H. spicatum, respectively. The
absorbance for reducing power was found to be 0.540, 0.036, 0.042, 0.046, 0.050
and 0.072 for ascorbic acid, petroleum ether, benzene, chloroform, methanol and
aqueous extracts of rhizomes of H. spicatum, respectively. Total phenol
content was found to be 13, 33, 24, 32 and 35 mg equivalent to gallic acid per
gram of petroleum ether, benzene, chloroform, methanol and aqueous extracts of
rhizomes of H. spicatum, respectively. Total flavonoid content was found
to be 4.6, 7, 7.5, 34.5 and 40 mg equivalent to rutin per gram of petroleum
ether, benzene, chloroform, methanol and aqueous extracts of rhizomes of H.
spicatum, respectively. The strongest antioxidant activity of the methanol
and aqueous extracts could be due to the presence of flavonoids and phenols. |
| Page(s): | 354-358 |
| CC License: | CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0976-0512 (Online); 0976-0504 (Print) |
| Source: | IJNPR Vol.3(3) [September 2012]
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