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|Title:||Effect of Pinus massoniana Lamb. bark extract on lytic cycle of Epstein-Barr virus|
|Keywords:||Bark extract;Epstein-Barrr virus;EA-D;Lytic cycle;Pinus massoniana;Rta;Zta|
|Abstract:||Pinus massoniana bark extract (PMBE) at a concentration of 60 μg/mL or more inhibits the expression of Epstein–Barr virus (EBV) lytic proteins, such as Rta, Zta, and EA-D. EBV lytic cycle was blocked by inhibiting the transcription of immediate-early genes. The results suggest that the PMBE has anti-EBV activity. Thus, the extract is potentially useful in preventing the lytic development of EBV in vitro.|
|ISSN:||0975-1009 (Online); 0019-5189 (Print)|
|Appears in Collections:||IJEB Vol.50(10) [October 2012]|
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