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Title: Effect of Pinus massoniana Lamb. bark extract on lytic cycle of Epstein-Barr virus
Authors: Xu, Shuxia
Zhang, Shimin
Wang, Xuedong
Gao, Yuqian
Qin, Xing
Wu, Kun
Keywords: Bark extract;Epstein-Barrr virus;EA-D;Lytic cycle;Pinus massoniana;Rta;Zta
Issue Date: Oct-2012
Publisher: NISCAIR-CSIR, India
Abstract: Pinus massoniana bark extract (PMBE) at a concentration of 60 μg/mL or more inhibits the expression of Epstein–Barr virus (EBV) lytic proteins, such as Rta, Zta, and EA-D. EBV lytic cycle was blocked by inhibiting the transcription of immediate-early genes. The results suggest that the PMBE has anti-EBV activity. Thus, the extract is potentially useful in preventing the lytic development of EBV in vitro.
Page(s): 708-713
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.50(10) [October 2012]

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