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Title: <span style="font-size: 11.0pt;mso-bidi-font-size:15.0pt;font-family:"Times New Roman";mso-fareast-font-family: "Times New Roman";letter-spacing:-.1pt;mso-ansi-language:EN-GB;mso-fareast-language: EN-US;mso-bidi-language:AR-SA" lang="EN-GB">Effect of <i>Pinus massoniana</i> Lamb. bark extract on lytic cycle of Epstein-Barr virus</span>
Authors: Xu, Shuxia
Zhang, Shimin
Wang, Xuedong
Gao, Yuqian
Qin, Xing
Wu, Kun
Keywords: Bark extract
Epstein-Barrr virus
Lytic cycle
<i><span style="font-size:11.0pt;mso-bidi-font-size: 10.0pt;font-family:"Times New Roman";mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-GB;mso-fareast-language:EN-US;mso-bidi-language:AR-SA" lang="EN-GB">Pinus massoniana</span></i>
Issue Date: Oct-2012
Publisher: NISCAIR-CSIR, India
Abstract: <i>Pinus massoniana</i> bark extract (PMBE) at a concentration of 60 μg/mL or more inhibits the expression of Epstein–Barr virus (EBV) lytic proteins, such as Rta, Zta, and EA-D. EBV lytic cycle was blocked by inhibiting the transcription of immediate-early genes. The results suggest that the PMBE has anti-EBV activity. Thus, the extract is potentially useful in preventing the lytic development of EBV <i style="mso-bidi-font-style:normal">in vitro</i>.
Description: 708-713
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.50(10) [October 2012]

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