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Title: Synthesis and evaluation of some novel 2,4-thiazolidinedione derivatives for antibacterial, antitubercular and antidiabetic activities
Authors: Pattan, Shashikant
Kedar, Manisha
Pattan, Jayashri
Dengale, Santosh
Sanap, Manjusha
Gharate, Utkarsha
Shinde, Punam
Kadam, Sushma
Keywords: 2,4-Thiazolidinedione
Issue Date: Sep-2012
Publisher: NISCAIR-CSIR, India
Abstract: A series of 2,4-thiazolidinedione have been synthesized and evaluated for antibacterial, antitubercular and antidiabetic activities. The newly synthesized compounds have been characterized by IR, <sup>1</sup>H NMR and elemental analysis. All compounds have shown promising antibacterial, antitubercular and antidiabetic activities when compared with standard drug Norfloxacin, Streptomycin, and Glibenclamide respectively. Compounds <b>1a, 2a</b> have shown promising antibacterial activity while compounds <b>1b, 2b </b>have shown promising antitubercular activity and compounds <b style="mso-bidi-font-weight:normal">1a</b>, <b style="mso-bidi-font-weight:normal">2a</b> and <b style="mso-bidi-font-weight: normal">2c</b> have shown promising antidiabetic activity.
Description: 1421-1425
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.51B(09) [September 2012]

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