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Title: Synthesis and evaluation of some novel 2,4-thiazolidinedione derivatives for antibacterial, antitubercular and antidiabetic activities
Authors: Pattan, Shashikant
Kedar, Manisha
Pattan, Jayashri
Dengale, Santosh
Sanap, Manjusha
Gharate, Utkarsha
Shinde, Punam
Kadam, Sushma
Keywords: 2,4-Thiazolidinedione;Antibacterial;Antidiabetic;Antitubercular
Issue Date: Sep-2012
Publisher: NISCAIR-CSIR, India
Abstract: A series of 2,4-thiazolidinedione have been synthesized and evaluated for antibacterial, antitubercular and antidiabetic activities. The newly synthesized compounds have been characterized by IR, 1H NMR and elemental analysis. All compounds have shown promising antibacterial, antitubercular and antidiabetic activities when compared with standard drug Norfloxacin, Streptomycin, and Glibenclamide respectively. Compounds 1a, 2a have shown promising antibacterial activity while compounds 1b, 2b have shown promising antitubercular activity and compounds 1a, 2a and 2c have shown promising antidiabetic activity.
Page(s): 1421-1425
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.51B(09) [September 2012]

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