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IJC-B Vol.51B [2012] >
IJC-B Vol.51B(09) [September 2012] >


Title: Synthesis and cytotoxicity of new quinoline derivatives
Authors: Meshram, H M
Reddy, B Chennakesava
Kumar, D Aravind
Kalyan, M
Ramesh, P
Kavitha, P
Rao, J Venkateswara
Keywords: Quinolines
Suzuki protocol
Anticancer activity
Issue Date: Sep-2012
Publisher: NISCAIR-CSIR, India
Abstract: New 2,8-bis(trifluoromethyl)-4-substituted quinolines have been synthesized from 4-haloquinoline following the Suzuki protocol and N-arylation. The cytotoxicity of the synthesized compounds has been evaluated against human cancer cell lines, and among them, compounds 5a and 5g are found to be the more potent antiproliferative agents.
Page(s): 1411-1416
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.51B(09) [September 2012]

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