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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.51B [2012] >
IJC-B Vol.51B(09) [September 2012] >
| Title: | Synthesis and cytotoxicity of new quinoline derivatives |
| Authors: | Meshram, H M
Reddy, B Chennakesava
Kumar, D Aravind
Kalyan, M
Ramesh, P
Kavitha, P
Rao, J Venkateswara |
| Keywords: | Quinolines
Suzuki protocol
Anticancer activity |
| Issue Date: | Sep-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | New
2,8-bis(trifluoromethyl)-4-substituted quinolines have been synthesized from
4-haloquinoline following the Suzuki protocol and N-arylation. The cytotoxicity
of the synthesized compounds has been evaluated against human cancer cell
lines, and among them, compounds 5a
and 5g are found to be the more
potent antiproliferative agents. |
| Page(s): | 1411-1416 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.51B(09) [September 2012]
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