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Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.50 [2012] >
IJEB Vol.50(09) [September 2012] >
| Title: | Protective effects of subchronic caffeine administration on cisplatin induced urogenital toxicity in male mice |
| Authors: | Khazaei, M
Bayat, P D
Ghanbari, A
Khazaei, S
Feizian, M
Khodaei, A
Alian, H A S |
| Keywords: | Apoptosis
Caffeine
Cisplatin
Mice
TUNEL |
| Issue Date: | Sep-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | In Cisplatin treated group, the degeneration
intensity of the kidneys the diameter of seminiferous tubules as well as the
apoptotic index in testes and kidney were increased. In Caffeine+Cisplatin treated
groups, the total body weight, the weight of testes and kidneys and also the
histopathological data did not show significant differences. The motility of
sperm in cisplatin group reduced but in Caffeine+Cisplatin groups this
parameter was increased. These data suggest that caffeine recovers toxicity
induced by cisplatin in both kidneys and testes of mice.
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| Page(s): | 638-644 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.50(09) [September 2012]
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