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Title: Green synthesis of novel isoxazoline derivatives using N-methyl-α-chloro nitrone and their antibacterial activities
Authors: Chakraborty, Bhaskar
Sharma, Prawin Kumar
Samanta, Amalesh
Keywords: Cycloaddition reaction;Novel isoxazolines;Diastereo¬selectivity;MWI;Antibacterial activity
Issue Date: Aug-2012
Publisher: NISCAIR-CSIR, India
Abstract: Microwave assisted 1,3-dipolar cycloaddition reaction of N-methyl-α-chloro nitrone with various alkynes as dipolarophile have been studied and found to afford diastereomeric novel isoxazoline derivatives with high selectivity. All the synthesized compounds have been screened for their antibacterial activity and are found to exihibit significant activity.
Page(s): 1180-1185
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.51B(08) [August 2012]

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