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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.51B [2012] >
IJC-B Vol.51B(08) [August 2012] >
| Title: | Synthesis and biological evaluation of some new bipyrazolylbenzenesulfonamides as possible antimicrobial and chemotherapeutic agents |
| Authors: | Faidallah, Hassan M
Khan, Khalid A
Asiri, Abdullah M
Zayed, Mohie E M |
| Keywords: | Pyrazoles
Bipyrazoles
Bipyrazolebenzensulfonamides
Thiazolidines |
| Issue Date: | Aug-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A series of functionalized bipyrazoles,
fused bipyrazoles and other related heterocyclic systems have been synthesized.
The key intermediate bipyrazoles have been prepared by cyclocondensation of the
appropriate chalcone with
4-hydrazinobenzenesulfonamide hydrochloride. The chemistry of the
reactions employed in the synthesis of the target compounds together with their
chemical behaviour, are discussed and the structures of the newly synthesized
compounds have been confirmed by the IR and 1H and 13C
NMR spectral data. All the synthesized
compounds show weak anticancer activity and weak antimicrobial and antifungal
activity against some bacteria and fungi. |
| Page(s): | 1114-1122 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.51B(08) [August 2012]
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