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DC Field | Value | Language |
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dc.contributor.author | Balakumar, C | - |
dc.contributor.author | Kishore, D Pran | - |
dc.contributor.author | Rao, K Venkat | - |
dc.contributor.author | Narayana, B Lakshmi | - |
dc.contributor.author | Rajwinder, K | - |
dc.contributor.author | Rajkumar, V | - |
dc.contributor.author | Rao, A Raghuram | - |
dc.date.accessioned | 2012-08-06T07:28:58Z | - |
dc.date.available | 2012-08-06T07:28:58Z | - |
dc.date.issued | 2012-08 | - |
dc.identifier.issn | 0975-0983(Online); 0376-4699(Print) | - |
dc.identifier.uri | http://hdl.handle.net/123456789/14508 | - |
dc.description | 1105-1113 | en_US |
dc.description.abstract | A series of new 4H-pyrimido[2,1-b]benzothiazole-2-arylamino-3-cyano-4-ones 6a-g have been designed and synthesized by the application of microwave-assisted organic synthesis (MAOS) technique. In silico docking studies have been carried out to gain an insight into the hypothetical binding motif of the title compounds using a homology model of A2B adenosine receptor employing GOLD (CCDC, 4.0.1 version) software. The binding modes are proposed on the basis of molecular docking studies. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | NISCAIR-CSIR, India | en_US |
dc.rights | ![]() | en_US |
dc.source | IJC-B Vol.51B(08) [August 2012] | en_US |
dc.subject | 4H-pyrimido[2,1-b]benzothiazole-4-one | en_US |
dc.subject | Adenosine receptor antagonists | en_US |
dc.subject | docking studies | en_US |
dc.subject | Microwave-assisted organic synthesis | en_US |
dc.subject | GOLD | en_US |
dc.title | Design, microwave-assisted synthesis and in silico docking studies of new 4H-pyrimido[2,1-b]benzothiazole-2-arylamino-3-cyano-4-ones as possible adenosine A2B receptor antagonists | en_US |
dc.type | Article | en_US |
Appears in Collections: | IJC-B Vol.51B(08) [August 2012] |
Files in This Item:
File | Description | Size | Format | |
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IJCB 51B(8) 1105-1113.pdf | 174.61 kB | Adobe PDF | View/Open |
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