NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)]
 >
IJNPR Vol.3 [2012] >
IJNPR Vol.3(2) [June 2012] >


Title: Phenolic profiles, antimicrobial and antioxidant potentiality of methanolic extract of a liverwort, Plagiochila beddomei Steph.
Authors: Manoj, G S
Murugan, K
Keywords: Antimicrobial
Antioxidant
Bryophyte
Flavonoids
Liverwort
Plagiochila beddomei
Phenols
Issue Date: Jun-2012
Publisher: NISCAIR-CSIR, India
IPC CodeInt. cl. (2011.01)-A61K 36/10, A61P 31/00, A61P 39/06
Abstract: The present study was carried out to evaluate antioxidant and antimicrobial activities of methanol extract of Plagiochila beddomei Steph. - a liverwort (Bryophyte). Total phenolics was fractionated by high performance liquid chromatography, showed the presence of a pool of phenolic acids such as coumaric, ferulic, gallic, caffeic, protocatechol, cinnamic, sinapate, chlorogenate and hydroxyl benzoate. Methanolic extract showed broad spectrum antimicrobial activity against various bacteria such as Salmonella typhimurium, Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli, Bacillus cereus, B. subtilis, Proteus vulgaris, Pseudomonas aeruginosa and fungi like Candida albicans, Cryptococcus neoformans, Trichophyton rubrum, Aspergillus niger, A. flavus, A. terreus and Mucor indicus. Survivorship curve of bacteria and fungal spore germination were also analyzed. P.beddomei displayed significant antioxidant activity evaluated by 1,1-diphenyl- 2-picrylhydrazyl free radical-scavenging ability, ferric-reducing antioxidant power, ferric thiocyannate assay and hydroxyl radical-scavenging activity. Phenols and flavonoids were found to be present in high levels. Total phenol content was shown to provide the highest correlation with FRAP assay (R2 0.966). MTT assay revealed the non-toxic nature of the extract.
Page(s): 173-183
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Source:IJNPR Vol.3(2) [June 2012]

Files in This Item:

File Description SizeFormat
IJNPR 3(2) 173-183.pdf643.98 kBAdobe PDFView/Open
 Current Page Visits: 433 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 558802 since 06-Feb-2009  Last updated on 30-Jul-2014Webmaster: nopr@niscair.res.in