|
NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)] >
IJNPR Vol.3 [2012] >
IJNPR Vol.3(2) [June 2012] >
| Title: | Macro-microscopic evaluation and HPTLC-densitometric analysis of solasodine from fruits of some medicinally important species in genus Solanum Linn |
| Authors: | Upadhye, A S Kumbhalkar, B B Deshpande, A S |
| Keywords: | Authentication Fruits HPTLC Solanum sp. Solanaceae Solasodine Steroidal drugs. |
| Issue Date: | Jun-2012 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int. cl. (2011.01)-A61K 36/81, A61K 131/00 |
| Abstract: | Fruits of Solanum Linn. (Family ¾ Solanaceae) species, viz. S. anguivi Lam., S. nigrum Linn., S. melongena
Linn.,
S. virginianum Linn. and S. torvum Sw. are used in Indian traditional
system of medicine for diverse pharmacological activities. These fruits are
foremost source of solasodine which is one of the major starting materials used
for commercial synthesis of steroidal drugs.
In the present
study, comparative micro-morphology of fruits of above five species and
estimation of active principle
solasodine with HPTLC-densitometric method has been carried out. An artificial
key based on macroscopic and microscopic characters were developed for
identification and authentication of fruits. The trend of solasodine content
was as:
S. virginianum > S. nigrum > S. torvum > S. anguivi >
S. melongena. This data is helpful in identification and authentication of
plant samples and quantification of the active marker solasodine.
|
| Page(s): | 166-172 |
| CC License: | CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0976-0512 (Online); 0976-0504 (Print) |
| Source: | IJNPR Vol.3(2) [June 2012]
|
|