Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/14415
Title: <span style="font-size:11.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-bidi-font-family: Mangal;mso-ansi-language:EN-GB;mso-fareast-language:EN-US;mso-bidi-language: HI" lang="EN-GB">Phytochemical screening and antimicrobial activity of the leaves of <i>Hugonia mystax</i> Linn. (Linaceae)</span>
Authors: Vimalavady, A
Kadavul, K
Keywords: Antibacterial
Antifungal
Gram negative bacteria
Gram positive bacteria
<i>Hugonia mystax</i>
Phenolic compound
Phytochemical
Terpenoids
Issue Date: Jun-2012
Publisher: NISCAIR-CSIR, India
Series/Report no.: Int. cl. (2011.01)-A61K 36/55, A61K 127/00, A61P 31/00
Abstract: <i><span style="font-size:11.0pt;font-family: " times="" new="" roman";mso-fareast-font-family:"times="" roman";mso-bidi-font-family:="" mangal;letter-spacing:-.1pt;mso-ansi-language:en-gb;mso-fareast-language:en-us;="" mso-bidi-language:hi"="" lang="EN-GB">Hugonia mystax </span></i><span style="font-size:11.0pt;font-family:" times="" new="" roman";mso-fareast-font-family:="" "times="" roman";mso-bidi-font-family:mangal;letter-spacing:-.1pt;mso-ansi-language:="" en-gb;mso-fareast-language:en-us;mso-bidi-language:hi"="" lang="EN-GB">Linn<i>.</i> (Family <span style="font-size:11.0pt;font-family:Symbol;mso-ascii-font-family: " times="" new="" roman";mso-fareast-font-family:"times="" roman";mso-hansi-font-family:="" "times="" roman";mso-bidi-font-family:mangal;letter-spacing:-.1pt;mso-ansi-language:="" en-gb;mso-fareast-language:en-us;mso-bidi-language:hi;mso-char-type:symbol;="" mso-symbol-font-family:symbol"="" lang="EN-GB">¾<span style="font-size:11.0pt;font-family: " times="" new="" roman";mso-fareast-font-family:"times="" roman";mso-bidi-font-family:="" mangal;letter-spacing:-.1pt;mso-ansi-language:en-gb;mso-fareast-language:en-us;="" mso-bidi-language:hi"="" lang="EN-GB"> Linaceae) is a woody evergreen species. The leaves of this species are used for skin diseases and rheumatism. The present investigation was carried out to evaluate the phytochemical screening and antimicrobial activity of petroleum ether, chloroform and ethanol extracts of the leaves of <i>H. mystax.</i> Preliminary phytochemical screening of the plant revealed the presence of carbohydrates, flavonoids, saponins, phenolic compounds and terpenoids in the leaf extracts. Antimicrobial activity was studied using Agar well (10 mm diam) diffusion method and the diameter of inhibition zone was reported in millimeters. All the extracts showed moderate to very good activity against the Gram negative bacteria, viz. <i>Escherichia coli</i>, <i>Proteus vulgaris, Pseudomonas aeruginosa,</i> <i>Salmonella typhi</i>, <i>Vibrio parahaemolyticus </i>and<i> V. vulnificus</i>. The Gram positive bacteria like <i>Bacillus subtilis</i>, <i>Staphylococcus aureus</i> and <i>Streptococcus pneumoniae</i> were compared with the standard drug. Antifungal activity was studied against the organisms such as <i>Aspergillus flavus, A. fumigatus, A. niger</i> and <i>Candida albicans </i>and was compared with the respective standard drug.</span></span></span>
Description: 161-165
URI: http://hdl.handle.net/123456789/14415
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.3(2) [June 2012]

Files in This Item:
File Description SizeFormat 
IJNPR 3(2) 161-165.pdf133.4 kBAdobe PDFView/Open


Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.