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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
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Research Journals >
Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)] >
IJNPR Vol.3 [2012] >
IJNPR Vol.3(2) [June 2012] >
| Title: | Phytochemical screening and antimicrobial activity of the leaves of Hugonia mystax Linn. (Linaceae) |
| Authors: | Vimalavady, A
Kadavul, K |
| Keywords: | Antibacterial
Antifungal
Gram negative bacteria
Gram positive bacteria
Hugonia mystax
Phenolic compound
Phytochemical
Terpenoids |
| Issue Date: | Jun-2012 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int. cl. (2011.01)-A61K 36/55, A61K 127/00, A61P 31/00 |
| Abstract: | Hugonia mystax Linn. (Family ¾ Linaceae) is a woody evergreen species. The leaves of
this species are used for skin diseases and rheumatism. The present
investigation was carried out to evaluate the phytochemical screening and
antimicrobial activity of petroleum ether, chloroform and ethanol extracts of
the leaves of H. mystax. Preliminary phytochemical screening of the
plant revealed the presence of carbohydrates, flavonoids, saponins, phenolic
compounds and terpenoids in the leaf extracts. Antimicrobial activity was
studied using Agar well (10 mm diam) diffusion method and the diameter of
inhibition zone was reported in millimeters. All the extracts showed moderate
to very good activity against the Gram negative bacteria, viz. Escherichia
coli, Proteus vulgaris, Pseudomonas aeruginosa, Salmonella typhi,
Vibrio parahaemolyticus and V. vulnificus. The Gram positive
bacteria like Bacillus subtilis, Staphylococcus aureus and Streptococcus
pneumoniae were compared with the standard drug. Antifungal activity was
studied against the organisms such as Aspergillus flavus, A. fumigatus, A. niger
and Candida albicans and was compared with the respective standard drug. |
| Page(s): | 161-165 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0976-0512 (Online); 0976-0504 (Print) |
| Source: | IJNPR Vol.3(2) [June 2012]
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