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Title: Phytochemical screening and antimicrobial activity of the leaves of Hugonia mystax Linn. (Linaceae)
Authors: Vimalavady, A
Kadavul, K
Keywords: Antibacterial;Antifungal;Gram negative bacteria;Gram positive bacteria;Hugonia mystax;Phenolic compound;Phytochemical;Terpenoids
Issue Date: Jun-2012
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl. (2011.01)-A61K 36/55, A61K 127/00, A61P 31/00
Abstract: Hugonia mystax Linn. (Family ¾ Linaceae) is a woody evergreen species. The leaves of this species are used for skin diseases and rheumatism. The present investigation was carried out to evaluate the phytochemical screening and antimicrobial activity of petroleum ether, chloroform and ethanol extracts of the leaves of H. mystax. Preliminary phytochemical screening of the plant revealed the presence of carbohydrates, flavonoids, saponins, phenolic compounds and terpenoids in the leaf extracts. Antimicrobial activity was studied using Agar well (10 mm diam) diffusion method and the diameter of inhibition zone was reported in millimeters. All the extracts showed moderate to very good activity against the Gram negative bacteria, viz. Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa, Salmonella typhi, Vibrio parahaemolyticus and V. vulnificus. The Gram positive bacteria like Bacillus subtilis, Staphylococcus aureus and Streptococcus pneumoniae were compared with the standard drug. Antifungal activity was studied against the organisms such as Aspergillus flavus, A. fumigatus, A. niger and Candida albicans and was compared with the respective standard drug.
Page(s): 161-165
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.3(2) [June 2012]

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