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Title: A preliminary investigation of Turmeric-Agar composite film as bioactive wound dressing material on excision wound in rat model
Authors: Saraswathy, N
Rohit, R
Shanmugam, K
Sozheeswari, S Charanya
Ramalingam, P
Keywords: Antibacterial;Curcuma longa;Turmeric;Turmeric-Agar film;Wound dressing material
Issue Date: Jun-2012
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl. (2011.01)-A61K 36/00, A61P 17/02, A61F 13/00
Abstract: Curcuma longa Linn. is used in herbal medicines as antiseptic for wound healing. The objective of the present study is to investigate the turmeric impregnated agar film as bioactive wound dressing material. The turmeric-agar composite film was prepared by mixing, the acetone or methanol extract of turmeric powder and agar added with or without gelatin, glycerol, propylene glycol as additives. Physical and mechanical properties of the film were tested for its suitability for wound coverage. The antibacterial activity test of the film showed significant reduction in cell density as compared to the control. Turmeric-agar composite film applied wound showed complete epithelization by 11 days for turmeric-agar with acetone extract whereas 10 days for turmeric-agar with methanol extract when compared to 14 days in the control.
Page(s): 237-241
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.3(2) [June 2012]

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