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Title: <span style="font-size:12.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-ansi-language: EN-GB;mso-fareast-language:EN-US;mso-bidi-language:AR-SA" lang="EN-GB">Fuller’s earth catalyzed rapid synthesis of bis(indolyl)methanes under solvent free condition</span>
Authors: Kapuriya, Naval
Kakadiya, Rajesh
Savant, Mahesh M
Pansuriya, Akshay M
Bhuva, Chirag V
Patel, Anil S
Pipaliya, Piyush V
Audichya, Vipul B
Gangadharaiah, Sarala
Anandalwar, Sridhar M
Prasad, Javaregowda S
Shah, Anamik
Naliapara, Yogesh T
Keywords: Fuller’s earth
Electrophilic addition
Water mediated
Solvent free condition
Issue Date: Jul-2012
Publisher: NISCAIR-CSIR, India
Abstract: <span style="font-size:12.0pt;font-family: " times="" new="" roman";mso-fareast-font-family:"times="" roman";mso-ansi-language:="" en-gb;mso-fareast-language:en-us;mso-bidi-language:ar-sa"="" lang="EN-GB">A rapid and highly efficient synthesis of various bis(indolyl)methanes with high yield by the reaction of indoles <b style="mso-bidi-font-weight:normal">1a-c</b> and arylaldehydes <b style="mso-bidi-font-weight:normal">2a'-m'</b> in presence of fuller’s earth is demonstrated. <span style="font-size:12.0pt;font-family:" times="" new="" roman";="" mso-fareast-font-family:"times="" roman";mso-ansi-language:pl;mso-fareast-language:="" en-us;mso-bidi-language:ar-sa"="" lang="PL">This simple and versatile protocol is found to be an efficient catalyst for the electrophilic addition reaction of indole and works well under solvent free condition as well as in aqueous medium. The structure of newly synthesized compound <b style="mso-bidi-font-weight:normal">3m</b> has been confirmed by single crystal X-ray crystallography.</span></span>
Description: 1032-1038
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.51B(07) [July 2012]

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