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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.51B [2012] >
IJC-B Vol.51B(07) [July 2012] >
| Title: | Fuller’s earth catalyzed rapid synthesis of bis(indolyl)methanes under solvent free condition |
| Authors: | Kapuriya, Naval
Kakadiya, Rajesh
Savant, Mahesh M
Pansuriya, Akshay M
Bhuva, Chirag V
Patel, Anil S
Pipaliya, Piyush V
Audichya, Vipul B
Gangadharaiah, Sarala
Anandalwar, Sridhar M
Prasad, Javaregowda S
Shah, Anamik
Naliapara, Yogesh T |
| Keywords: | Fuller’s earth
Electrophilic addition
Bis(indolyl)¬methanes
Water mediated
Solvent free condition |
| Issue Date: | Jul-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A rapid and highly
efficient synthesis of various bis(indolyl)methanes with high yield by the reaction
of indoles 1a-c and arylaldehydes 2a'-m' in presence of fuller’s earth is
demonstrated. This simple and versatile protocol is found to
be an efficient catalyst for the electrophilic addition reaction of indole and
works well under solvent free condition as well as in aqueous medium. The
structure of newly synthesized compound 3m
has been confirmed by single crystal X-ray crystallography. |
| Page(s): | 1032-1038 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.51B(07) [July 2012]
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