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Title: An efficient, inexpensive ‘Green Chemistry’ route to multicomponent Biginelli condensation catalyzed by CuCl₂.2H₂O-HCl
Authors: Pathak, Vijai Nath
Gupta, Ragini
Varshney, Bindu
Keywords: Dihydropyrimidinones;Biginelli condensation;Solvent free;Grindstone chemistry;CuCl2.2H2O-Conc. HCl;Green chemistry
Issue Date: Mar-2008
Publisher: CSIR
Abstract: Several Biginelli compounds (dihydropyrimidinones) have been synthesized efficiently and in high yields under mild, solvent-free and eco-friendly conditions by using ‘Grindstone Chemistry Technique’ catalyzed by CuCl₂.2H₂O and Conc. HCl. The obtained products have been identified by comparison with authentic samples (synthesized by conventional process) and by spectral (¹H NMR and IR) data and their melting points.
Page(s): 434-438
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.47B(03) [March 2008]

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