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IJEB Vol.50(06) [June 2012] >


Title: Antistress activity of ethanolic extract of Asparagus racemosus Willd roots in mice
Authors: Joshi, Tanuj
Sah, Sangeeta P
Singh, Anita
Keywords: Antistress
Asparagus racemosus
Restraint stress
Root extract
Saponins
Issue Date: Jun-2012
Publisher: NISCAIR-CSIR, India
Abstract: Ethanolic extract of the roots of A. racemosus improved the stress tolerance in chemical writhing test and swimming endurance test at all the doses as compared to stress control group. Restraint stress induced elevation of blood glucose, triglyceride and cholesterol levels were significantly lowered by pretreatment with extract. Moreover, stress induced variations in levels of lipid peroxidation, nitric oxide, protein and glutathione content in mouse brain were significantly ameliorated by pretreatment with extract. The extract attenuated the elevated weight of adrenal glands and increased the reduced weight of the spleen during stress. In conclusion, the results suggest antistress property of Asparagus racemosus in different model of stress.
Page(s): 419-424
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Source:IJEB Vol.50(06) [June 2012]

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