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Title: Formulation and evaluation of sublingual tablets of lisinopril
Authors: Grover, Ish
Agarwal, Gaurav
Keywords: Bioavailability;Faster disintegration;Hypertension;Sublingual route
Issue Date: Jun-2012
Publisher: NISCAIR-CSIR, India
Abstract: This study presents formulation and evaluation of sublingual tablets of lisinopril for treatment of hypertension. Sublingual route offers faster disintegration and dissolution of drug than oral route, because of increasing bioavailability as it bypass GIT (gastro intestinal tract). Sublingual tablets, prepared by direct compression method, were found in accordance with standards. Out of three batches (A, B, C), batch B having fastest disintegrating time was most suitable as sublingual tablet.
Page(s): 413-417
ISSN: 0975-1084 (Online); 0022-4456 (Print)
Appears in Collections:JSIR Vol.71(06) [June 2012]

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