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Journal of Scientific and Industrial Research (JSIR) >
JSIR Vol.71 [2012] >
JSIR Vol.71(06) [June 2012] >
| Title: | Formulation and evaluation of sublingual tablets of lisinopril |
| Authors: | Grover, Ish
Agarwal, Gaurav |
| Keywords: | Bioavailability
Faster disintegration
Hypertension
Sublingual route |
| Issue Date: | Jun-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | This study presents formulation and evaluation of sublingual tablets of lisinopril for treatment of hypertension. Sublingual route offers faster disintegration and dissolution of drug than oral route, because of increasing bioavailability as it bypass GIT (gastro intestinal tract). Sublingual tablets, prepared by direct compression method, were found in accordance with standards. Out of three batches (A, B, C), batch B having fastest disintegrating time was most suitable as sublingual tablet. |
| Page(s): | 413-417 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1084 (Online); 0022-4456 (Print) |
| Source: | JSIR Vol.71(06) [June 2012]
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