NISCAIR Online Periodicals Repository

Research Journals >
Journal of Scientific and Industrial Research (JSIR) >
JSIR Vol.71 [2012] >
JSIR Vol.71(06) [June 2012] >

Title: Sustained stomach specific delivery of piroxicam from floating emulsion polyelectrolyte complex beads
Authors: Verma, Anurag
Dixit, Raghav
Pandit, Jayant K
Keywords: Chitosan
Emulsion PEC beads
Floating drug delivery
Issue Date: Jun-2012
Publisher: NISCAIR-CSIR, India
Abstract: This study presents development of floating emulsion polyelectrolyte complex (PEC) beads based on gellan-chitosan PEC and Gelucire 39/01 and 50/13 without using any chemical crosslinker, and release from developed beads of piroxicam (PRM) in 0.1 M HCl (pH 1.2). Developed beads showed excellent buoyancy, significantly improved encapsulation efficiency and sustained release of PRM compared to floating gellan-chitosan beads bearing PRM. Thus emulsion PEC beads may form a potential stomach site specific drug delivery system for PRM delivery.
Page(s): 407-412
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-1084 (Online); 0022-4456 (Print)
Source:JSIR Vol.71(06) [June 2012]

Files in This Item:

File Description SizeFormat
JSIR 71(6) 407-412.pdf281.96 kBAdobe PDFView/Open
 Current Page Visits: 101 
Recommend this item


Online Submission of Articles |  NISCAIR Website |  National Knowledge Resources Consortium |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2015 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 172122 since 01-Sep-2015  Last updated on 30-Jun-2016Webmaster: