NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.47B [2008] >
IJC-B Vol.47B(02) [February 2008] >


Title: Reactions of 5-benzoyl-/5-carbaldehyde- /5-(3-phenyl-acryloyl)- 6-hydroxy-1H-pyrimidin- 2,4-diones with amines: Anti-cancer and metal sequestering properties
Authors: Singh, Palwinder
Kaur, Jatinder
Paul, Kamaldeep
Keywords: 5-Acylpyrimidines
Amine
Enamines
Anti-cancer activities
Metal chelators
Issue Date: Feb-2008
Publisher: CSIR
Abstract: Reactions of 5-benzoyl- / 5-carbaldehyde- / 5-(3-phenyl-acryloyl)-6-hydroxy-1H- pyrimidine-2,4-diones and diamines result in the formation of corresponding enamines. Appreciable anti-cancer activities of compounds 2, 5, 6 and 8 at various cell lines of 59 human tumor cell panels have been observed. UV spectral studies of these compounds in solution with Cu(OAc)₂ and FeCl₃ indicate their interactions with Cu⁺² and Fe⁺³ ions.
Page(s): 291-296
ISSN: 0376-4699
Source:IJC-B Vol.47B(02) [February 2008]

Files in This Item:

File Description SizeFormat
IJCB 47B(2) (2008) 291-296.pdf142.14 kBAdobe PDFView/Open
 Current Page Visits: 1061 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 603358 since 06-Feb-2009  Last updated on 21-Oct-2014Webmaster: nopr@niscair.res.in