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dc.contributor.authorSingh, G S-
dc.contributor.authorPheko, T-
dc.description.abstractTreatment of the 1,3,3-trisubstituted 4-[2'-(O-diarylacyl)hydroxyphenyl]-2-azetidinones with sodium hydroxide in ethanol at room temperature lead to selective cleavage of the ester linkage in the substrates forming new 1,3,3-trisubstituted 4-(2'-hydroxyphenyl)-2-azetidinones, which have been characterized on the basis of analytical and spectral (IR, ¹H and ¹³C NMR, MS) data. The structure elucidation also involves application of the HMQC and HMBC studies using 2-D NMR (¹H-¹³C COSY) spectra. The antibacterial and antifungal activities of the products are reported.en_US
dc.sourceIJCB Vol.47B(1) [January 2008]en_US
dc.subjectAntimicrobial activityen_US
dc.subjectHMQC studyen_US
dc.subjectHMBC studyen_US
dc.titleFormation and antimicrobial activity of 2-azetidinones from selective ester cleavage in 1,3,3-trisubstituted 4-[2-(O-diarylacyl) hydroxyphenyl]-2- azetidinonesen_US
Appears in Collections: IJC-B Vol.47B(01) [January 2008]

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