NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.47B [2008] >
IJC-B Vol.47B(01) [January 2008] >


Title: Formation and antimicrobial activity of 2-azetidinones from selective ester cleavage in 1,3,3-trisubstituted 4-[2-(O-diarylacyl) hydroxyphenyl]-2- azetidinones
Authors: Singh, G S
Pheko, T
Keywords: Azetidinones
Antimicrobial activity
HMQC study
HMBC study
Issue Date: Jan-2008
Publisher: CSIR
Abstract: Treatment of the 1,3,3-trisubstituted 4-[2'-(O-diarylacyl)hydroxyphenyl]-2-azetidinones with sodium hydroxide in ethanol at room temperature lead to selective cleavage of the ester linkage in the substrates forming new 1,3,3-trisubstituted 4-(2'-hydroxyphenyl)-2-azetidinones, which have been characterized on the basis of analytical and spectral (IR, ¹H and ¹³C NMR, MS) data. The structure elucidation also involves application of the HMQC and HMBC studies using 2-D NMR (¹H-¹³C COSY) spectra. The antibacterial and antifungal activities of the products are reported.
Page(s): 159-162
ISSN: 0376-4699
Source: IJC-B Vol.47B(01) [January 2008]

Files in This Item:

File Description SizeFormat
IJCB 47B(1) (2008) 159-162.pdf51.61 kBAdobe PDFView/Open
 Current Page Visits: 657 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 584359 since 06-Feb-2009  Last updated on 15-Sep-2014Webmaster: nopr@niscair.res.in