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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.47B [2008] >
IJC-B Vol.47B(01) [January 2008] >
| Title: | Synthesis and anti-tuberculosis activity of 2,4-disubstituted quinolines |
| Authors: | Nayyar, Amit
Jain, Rahul |
| Keywords: | Tuberculosis
Ring-substituted quinolines
Drug-sensitive TB
Drug-resistant TB
Multi-drug resistant TB
Extreme drug-resistant TB |
| Issue Date: | Jan-2008 |
| Publisher: | CSIR |
| Abstract: | Synthesis and anti-tuberculosis activity of a new series of 2,4-disubstituted quinolines have been reported. The most promising compounds have been found to exhibit 99% inhibition at 6.25 μg/mL against drug-sensitive M. tuberculosis H37Rν strain and >90% inhibition at 12.5 μg/mL against isoniazid resistant TB strain. |
| Page(s): | 117-128 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.47B(01) [January 2008]
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