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Title: Microwave accelerated synthesis of 2-aminothiophenes in ionic liquid via three component Gewald reaction
Authors: Chavan, Sunil S
Pedgaonkar, Yogesh Y
Jadhav, Ananda J
Degani, Mariam S
Keywords: Gewald Reaction;2-aminothiophenes;Ionic Liquid;Multicomponent Reaction;Microwave-Assisted Synthesis
Issue Date: Apr-2012
Publisher: NISCAIR-CSIR, India
Abstract: Microwave accelerated synthesis of substituted 2-amino¬≠thiophenes by a three-component Gewald reaction using a basic ionic liquid, 1,1,3,3-tetramethylguanidine lactate [TMG] [Lac] as solvent as well as catalyst has been developed. The products are obtained in good to high yields and the ionic liquid is reusable over several cycles without significant loss in catalytic activity.
Page(s): 653-657
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.51B(04) [April 2012]

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