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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
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Research Journals >
Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)] >
IJNPR Vol.3 [2012] >
IJNPR Vol.3(1) [March 2012] >
| Title: | In vitro antifungal activity of ethanol fractions of Argyreia nervosa (Burm. f.) Boj. leaves |
| Authors: | Mahule, Ajay
Rai, Pallavi
Ghorpade, Deepali S
Khadabadi, Somashekhar |
| Keywords: | Argyreia nervosa
HPTLC
Antifungal activity
Bio-autography
Fractionation |
| Issue Date: | Mar-2012 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int. cl. (2011.01)- A61K 36/00, A61P 31/10 |
| Abstract: | Argyreia nervosa (Burm. f.) Boj. has
been traditionally used in the treatment of skin infections. In the present
study, in vitro antifungal activity
of petroleum ether, benzene, ethyl acetate, chloroform fractions of ethanol
extract of leaves of
A. nervosa was performed.
Candida albicans, Aspergillus niger,
A. flavus, Trichoderma spp., Fusarium
proliferatum, Microsporum spp. and
Trichophyton spp. were the test organisms. The preliminary study was
performed using the disc diffusion method. The ethyl acetate fraction showed
significant antifungal activity as compared to other fractions. The MIC of the
ethyl acetate fraction was found to be in the range of 70-80 µg/ml. The
fractions were then analyzed with TLC
bio-autographic analysis. The antifungal components were identified by their Rf
values and these components showed positive tests for flavonoids.
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| Page(s): | 48-54 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0976-0512 (Online); 0976-0504 (Print) |
| Source: | IJNPR Vol.3(1) [March 2012]
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