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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)] >
IJNPR Vol.3 [2012] >
IJNPR Vol.3(1) [March 2012] >
| Title: | Phytochemical and antimicrobial screening of medicinal plants for the treatment of acne |
| Authors: | Nand, P
Drabu, S
Gupta, R K |
| Keywords: | Antimicrobial activity
Calendula officinalis
Camellia sinensis
Disc diffusion method
Glycyrrhiza glabra
Phytochemical screening |
| Issue Date: | Mar-2012 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int. cl. (2011.01)- A61K 36/00, A61P 31/10, A61P 17/10 |
| Abstract: | Extracts of Camellia sinensis Linn.
leaves, Glycyrrhiza glabra Linn. roots and rhizome and Calendula officinalis Linn. flowers were screened for their in vitro antimicrobial
activity using agar disc diffusion method. The antimicrobial activity of
petroleum ether, dichloromethane and methanolic extracts of different parts of
these plants were studied against acne causing bacteria, namely Staphylococcus aureus (MTCC 96),
Staphylococcus epidermidis (MTCC 2639) and Propionibacterium acnes
(MTCC *1951). Methanolic extract of C. sinensis leaves possessed highest
antibacterial activity against S. epidermidis. Lowest minimum inhibitory
concentration (0.625 mg/mL) and minimum bactericidal concentration (2.5
mg/mL) against S. epidermidis were also observed for methanolic extract
of C. sinensis leaves. Phytochemical screening revealed the presence of alkaloids, flavonoids,
glycosides and terpenoids which indicates that these
phytoconstituents may be responsible for their anti-acne activity.
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| Page(s): | 28-32 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0976-0512 (Online); 0976-0504 (Print) |
| Source: | IJNPR Vol.3(1) [March 2012]
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