Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/13803
Title: Phytochemical and antimicrobial screening of medicinal plants for the treatment of acne
Authors: Nand, P
Drabu, S
Gupta, R K
Keywords: Antimicrobial activity
<i><span style="font-size:11.0pt; mso-bidi-font-size:10.0pt;font-family:"Times New Roman","serif";mso-fareast-font-family: Arial;mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language: AR-SA" lang="EN-US">Calendula officinalis</span></i>
<i><span style="font-size:11.0pt; mso-bidi-font-size:10.0pt;font-family:"Times New Roman","serif";mso-fareast-font-family: Arial;mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language: AR-SA" lang="EN-US">Camellia sinensis</span></i>
Disc diffusion method
<i><span style="font-size:11.0pt; mso-bidi-font-size:10.0pt;font-family:" times="" new="" roman","serif";mso-fareast-font-family:="" arial;mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:="" ar-sa"="" lang="EN-US">Glycyrrhiza glabra</span></i>
Phytochemical screening
Issue Date: Mar-2012
Publisher: NISCAIR-CSIR, India
Series/Report no.: Int. cl. (2011.01)- A61K 36/00, A61P 31/10, A61P 17/10
Abstract: Extracts of<i> </i><i>Camellia sinensis </i><span style="mso-bidi-font-size:11.0pt;mso-fareast-font-family:Arial" lang="EN-GB">Linn<span style="mso-fareast-font-family:Arial;mso-bidi-font-style:italic" lang="EN-GB">. leaves<span style="mso-bidi-font-weight:bold" lang="EN-GB">,<b> </b><i>Glycyrrhiza </i><i style="mso-bidi-font-style:normal">glabra</i><b> </b><span style="mso-bidi-font-weight:bold" lang="EN-GB">Linn. roots and rhizome and<i> Calendula officinalis </i><span style="mso-fareast-font-family:Arial;mso-bidi-font-style:italic" lang="EN-GB">Linn. flowers were screened for their<i> in vitro</i> antimicrobial activity using agar disc diffusion method. The antimicrobial activity of petroleum ether, dichloromethane and methanolic extracts of different parts of these plants were studied against acne causing bacteria, namely <i>Staphylococcus aureus</i> (MTCC 96),<i> Staphylococcus epidermidis</i> (MTCC 2639) and <i>Propionibacterium acnes</i> (MTCC *1951). Methanolic extract of <i>C. sinensis</i> leaves possessed highest antibacterial activity against <i>S. epidermidis</i>. Lowest minimum inhibitory concentration (0.625 mg/mL) and minimum bactericidal concentration<i> </i>(2.5 mg/mL) against <i>S. epidermidis</i> were also observed for methanolic extract of <i>C. sinensis </i><span style="mso-bidi-font-style:italic">leaves. Phytochemical screening revealed the presence of alkaloids, flavonoids, glycosides and terpenoids which indicates that these phytoconstituents may be responsible for their anti-acne activity. </span></span></span></span></span></span>
Description: 28-32
URI: http://hdl.handle.net/123456789/13803
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.3(1) [March 2012]

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