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Title: Phytochemical and antimicrobial screening of medicinal plants for the treatment of acne
Authors: Nand, P
Drabu, S
Gupta, R K
Keywords: Antimicrobial activity;Calendula officinalis;Camellia sinensis;Disc diffusion method;Glycyrrhiza glabra;Phytochemical screening
Issue Date: Mar-2012
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl. (2011.01)- A61K 36/00, A61P 31/10, A61P 17/10
Abstract: Extracts of Camellia sinensis Linn. leaves, Glycyrrhiza glabra Linn. roots and rhizome and Calendula officinalis Linn. flowers were screened for their in vitro antimicrobial activity using agar disc diffusion method. The antimicrobial activity of petroleum ether, dichloromethane and methanolic extracts of different parts of these plants were studied against acne causing bacteria, namely Staphylococcus aureus (MTCC 96), Staphylococcus epidermidis (MTCC 2639) and Propionibacterium acnes (MTCC *1951). Methanolic extract of C. sinensis leaves possessed highest antibacterial activity against S. epidermidis. Lowest minimum inhibitory concentration (0.625 mg/mL) and minimum bactericidal concentration (2.5 mg/mL) against S. epidermidis were also observed for methanolic extract of C. sinensis leaves. Phytochemical screening revealed the presence of alkaloids, flavonoids, glycosides and terpenoids which indicates that these phytoconstituents may be responsible for their anti-acne activity.
Page(s): 28-32
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.3(1) [March 2012]

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