NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)]
 >
IJNPR Vol.3 [2012] >
IJNPR Vol.3(1) [March 2012] >


Title: Potentiality of aqueous leaf extract of Trichosanthes cucumerina Linn. on hair growth promotion in Wistar albino rats
Authors: Sandhya, S
Chandrasekhar, J
Vinod, K R
Banji, David
Keywords: Alopecia
Anagen
Bald patch
Hair follicles
Hair growth promoter
Minerals
Minoxidil
Snake gourd
Telogen
Trichosanthes cucumerina
Issue Date: Mar-2012
Publisher: NISCAIR-CSIR, India
IPC CodeInt. cl. (2011.01)- A61K 36/42, A61K 127/00, A61P 17/14
Abstract: Trichosanthes cucumerina Linn. (Snake gourd) is an annual climber which is widely distributed in Asian countries. It is a rich source of nutrition. The leaves of the plant are used by the folklore for alopecia. Hence, in the present investigation the hair growth promoting activity was evaluated on Wistar albino rats. The preliminary chemical screening of the aqueous extract revealed the presence of carbohydrates, flavonoids, saponins, flavonol glycoside and triterpenoid saponins. The animals were divided into four groups and the control group was applied with water, standard group with 2% Minoxidil and two test groups with 150 and 300 mg/kg of aqueous extract of T. cucumerina leaves. Qualitative and quantitative parameters were evaluated. It was observed that the hair growth completion, length of hair, percentage of hair follicles and diameter of bald patch and concentration of minerals in the blood for the test animals applied with 300 mg/kg drug was comparable with that of the animals treated with 2% Minoxidil. This study reveals that the leaves of T. cucumerina are a potent hair growth promoter which supports the traditional claim.
Page(s): 14-19
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Source:IJNPR Vol.3(1) [March 2012]

Files in This Item:

File Description SizeFormat
IJNPR 3(1) 14-19.pdf113.56 kBAdobe PDFView/Open
 Current Page Visits: 436 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 511369 since 06-Feb-2009  Last updated on 11-Apr-2014Webmaster: nopr@niscair.res.in