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Title: Phytochemical screening and antibacterial activity of Hemionitis arifolia (Burm.) Moore
Authors: Hima Bindu N, SVSSSL
Devi, P Suvarnalatha
Rukmini, K
Charya, M A Singara
Keywords: Hemionitis arifolia;Phytochemical screening;Antibacterial activity;Tirumala hills
Issue Date: Mar-2012
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl. (2011.01)—A61K 36/00, A61P 31/04
Abstract: Hemionitis arifolia (Burm.) Moore of family Hemionitidaceae is one of the endemic and widely distributed species on Tirumala hills of Tirupati, Andhra Pradesh, India. Ethnomedicinally, the genus is important and popularly known as Ramabanum. It has been used in burns, menstrual disorders, anti-flatulence and antifertility. Eight  different organic solvents were used to extract the bioactive compounds from the whole plant to screen the phytochemical and antibacterial activity against infectious disease causing bacterial pathogens such as Enterobacter aerogens, Klebsiella pnemoniae, Salmonella paratyphi A, Ralstonia eutropha, Salmonella typhi, Salmonella paratyphi B, Staphylococcus aureus, Bacillus cereus, Bacillus subtilis, Bacillus sphericus, Bacillus sterothermophilus and Micrococcus luteus by agar well diffusion method. Phytochemical screening showed the presence of flavonoid, steroids and glycosides along with reducing sugar in all the extracts investigated. Gram-negative bacteria such as Salmonella typhi, S. paratyphi A and Enterobacter aerogens were more susceptible to the crude extracts than Gram-positive bacteria. Hence, at any rate Hemionitis arifolia is an attractive material for further research leading to possible drug development.
Page(s): 9-13
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.3(1) [March 2012]

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